Theory 107/New facility/Neuroscience
Whole Connectome
The claim
Wiring principles cannot be inferred from partial connectomes because the cost-benefit trade-off is global, so a whole-brain map is required.
01Mechanism
Optimisation is over the whole network; subsets have different effective constraints.
02Prediction
Partial maps should suggest different principles than whole maps.
03Refutation
Consistent principles across subsets would remove the need.