Theory 20/Wound healing/Progression phase
Closure Is Granulation Against Contraction
The claim
How a wound closes is set by the ratio of granulation tissue formation to myofibroblast contraction, so the same wound closes differently in different sites.
01Mechanism
New tissue fills while contraction pulls edges; the ratio determines the mechanism.
02Prediction
Closure mode should track the ratio.
03Refutation
Closure tracking wound size would remove the mechanism balance.