Theory 22/Bone remodelling/Onset phase
Remodelling Starts on Damage
The claim
A remodelling cycle begins above a threshold in accumulated microdamage, so bone with light load cycles through fewer cycles per year.
01Mechanism
Osteocytes detect damage and signal resorption; the threshold sets the trigger.
02Prediction
Cycle frequency should track damage.
03Refutation
Cycle frequency tracking load would remove damage.