Theory 33/Cellular/Tumour growth
Growth Pattern Is Proliferation Against Invasion
The claim
Whether a tumour grows as a compact mass or an infiltrative one is set by the ratio of proliferation rate to invasion rate, so the same mutation can produce either depending on the tissue.
01Mechanism
Proliferation pushes outward while invasion moves cells into matrix; the ratio determines the front geometry.
02Prediction
Morphology should track the ratio.
03Refutation
Morphology tracking mutation alone would remove the rate balance.