Theory 34/Tissue/Oxygen transport
Penetration Is Supply Against Demand
The claim
The depth to which oxygen reaches in tissue is set by the ratio of diffusion length to consumption rate, so dense tissue becomes hypoxic at the same vascular spacing as sparse tissue.
01Mechanism
Oxygen diffuses from vessels while cells consume it; the profile falls exponentially with a length set by the ratio.
02Prediction
Hypoxic depth should track the ratio.
03Refutation
Depth tracking vascular spacing alone would remove consumption.