Theory 18/Hours to Days/Wound healing
Inflammation Must Hand Over
The claim
Wound inflammation resolves only if the ratio of neutrophil to macrophage arrival time is within a window, so either an early or a late macrophage wave prolongs inflammation.
01Mechanism
Neutrophils initiate and must be cleared by macrophages; if macrophages arrive too late, the neutrophil phase persists, and if too early, clearance is incomplete.
02Prediction
Resolution should track the timing ratio.
03Refutation
Resolution tracking cell numbers would remove the timing.