Theory 21/Weeks to Months/Fracture healing
Healing Needs Callus Before Load
The claim
Bone healing succeeds only if the ratio of callus formation time to loading onset is below a threshold, so early loading before callus is established prevents union.
01Mechanism
The callus must stabilise the fracture before physiological load is applied; if loading precedes it, micromotion disrupts the repair tissue.
02Prediction
Non-union should track the ratio.
03Refutation
Union tracking loading magnitude would remove timing.