Theory 58/Networks & Connectivity/Cognitive neuroscience
Hub Damage Costs More
The claim
Cognitive deficit after network damage is set by the ratio of lost hub degree to redundant pathways, so lesions of equal size differ by location.
01Mechanism
Hubs carry integrative traffic; if redundancy is low, their loss disconnects modules even when the lesion is small.
02Prediction
Deficit should track the ratio.
03Refutation
Deficit tracking lesion size would remove the topology.