Drug–gene catalogue

Historical supplied molecular/therapeutic catalogue columns only. Demographic coverage, ancestry and comparative frequency columns are omitted. Values are copied from the existing source snapshot; they are not a current prescribing recommendation.

Drug	Gene	CPIC level
abacavir	HLA-B	A
allopurinol	HLA-B	A
amikacin	MT-RNR1	A
amitriptyline	CYP2C19	A
amitriptyline	CYP2D6	A
atazanavir	UGT1A1	A
atomoxetine	CYP2D6	A
atorvastatin	SLCO1B1	A
azathioprine	TPMT	A
azathioprine	NUDT15	A
capecitabine	DPYD	A
carbamazepine	HLA-A	A
carbamazepine	HLA-B	A
celecoxib	CYP2C9	A
citalopram	CYP2C19	A
clomipramine	CYP2C19	B
clomipramine	CYP2D6	B
clopidogrel	CYP2C19	A
codeine	CYP2D6	A
dapsone	G6PD	A
desflurane	CACNA1S	A
desflurane	RYR1	A
desipramine	CYP2D6	B
dexlansoprazole	CYP2C19	B
dibekacin	MT-RNR1	A
doxepin	CYP2C19	B
doxepin	CYP2D6	B
efavirenz	CYP2B6	A
enflurane	CACNA1S	A
enflurane	RYR1	A
escitalopram	CYP2C19	A
fluorouracil	DPYD	A
flurbiprofen	CYP2C9	A
fluvastatin	SLCO1B1	A
fluvastatin	CYP2C9	A
fluvoxamine	CYP2D6	B
fosphenytoin	CYP2C9	A
fosphenytoin	HLA-B	A
gentamicin	MT-RNR1	A
halothane	CACNA1S	A
halothane	RYR1	A
hydralazine	NAT2	A
hydrocodone	CYP2D6	B
ibuprofen	CYP2C9	A
imipramine	CYP2C19	B
imipramine	CYP2D6	B
isoflurane	RYR1	A
isoflurane	CACNA1S	A
ivacaftor	CFTR	A
kanamycin	MT-RNR1	A
lansoprazole	CYP2C19	A
lornoxicam	CYP2C9	A
lovastatin	SLCO1B1	A
meloxicam	CYP2C9	A
mercaptopurine	TPMT	A
mercaptopurine	NUDT15	A
methoxyflurane	CACNA1S	A
methoxyflurane	RYR1	A
methylene blue	G6PD	A
metoprolol	CYP2D6	B
neomycin	MT-RNR1	A
netilmicin	MT-RNR1	A
nitrofurantoin	G6PD	A
nortriptyline	CYP2D6	A
omeprazole	CYP2C19	A
ondansetron	CYP2D6	A
oxcarbazepine	HLA-B	A
pantoprazole	CYP2C19	A
paromomycin	MT-RNR1	A
paroxetine	CYP2D6	A
pegloticase	G6PD	A
phenytoin	CYP2C9	A
phenytoin	HLA-B	A
piroxicam	CYP2C9	A
pitavastatin	SLCO1B1	A
plazomicin	MT-RNR1	A
pravastatin	SLCO1B1	A
primaquine	G6PD	A
rasburicase	G6PD	A
ribostamycin	MT-RNR1	A
rosuvastatin	ABCG2	A
rosuvastatin	SLCO1B1	A
sertraline	CYP2C19	A
sertraline	CYP2B6	B
sevoflurane	CACNA1S	A
sevoflurane	RYR1	A
simvastatin	SLCO1B1	A
streptomycin	MT-RNR1	A
succinylcholine	CACNA1S	A
succinylcholine	RYR1	A
tacrolimus	CYP3A5	A
tafenoquine	G6PD	A
tamoxifen	CYP2D6	A
tenoxicam	CYP2C9	A
thioguanine	NUDT15	A
thioguanine	TPMT	A
tobramycin	MT-RNR1	A
toluidine blue	G6PD	A
tramadol	CYP2D6	A
trimipramine	CYP2C19	B
trimipramine	CYP2D6	B
tropisetron	CYP2D6	A
venlafaxine	CYP2D6	B
voriconazole	CYP2C19	A
vortioxetine	CYP2D6	A
warfarin	CYP4F2	A
warfarin	VKORC1	A
warfarin	CYP2C9	A