Theory 31/Seizure cycle/Onset phase
Onset Is Excitation Against Inhibition
The claim
A seizure begins above a threshold in the ratio of excitation to inhibition, so identical excitation produces a seizure only when inhibition is low.
01Mechanism
Network excitability is the balance of the two; the ratio sets the threshold.
02Prediction
Onset should track the ratio.
03Refutation
Onset tracking excitation alone would remove inhibition.