Incoprea Theory
Vol. XXVI · 129

Theory 36/Migraine cycle/Termination phase

Pain Ends on Trigeminal Sensitisation

The claim

Headache resolution is set by the ratio of central sensitisation to descending inhibition, so the attack ends when inhibition recovers the balance.

01Mechanism

Sensitisation maintains pain; the ratio determines when it subsides.

02Prediction

Duration should track the ratio.

03Refutation

Duration tracking trigger strength would remove inhibition.