Incoprea Theory
Vol. XXVI · 129

Theory 27/Hair follicle cycle/Termination phase

Catagen Is Programmed Retraction

The claim

Growth ends when the ratio of apoptotic signal to survival signal crosses a threshold, and the club hair forms regardless of fibre length.

01Mechanism

The lower follicle regresses by apoptosis; the ratio determines initiation.

02Prediction

Catagen timing should track the ratio.

03Refutation

Catagen tracking fibre length would remove the signal.