Incoprea Theory
Vol. XXVI · 129

Theory 25/Hair follicle cycle/Onset phase

Anagen Starts on a Signal Ratio

The claim

A follicle enters growth above a threshold in the ratio of dermal papilla signal to inhibitory factor, so the same follicle cycles on a schedule set by that balance.

01Mechanism

Stem cell activation requires the activator to exceed the inhibitor; the ratio sets the timing.

02Prediction

Cycle timing should track the ratio.

03Refutation

Timing tracking follicle age would remove the balance.