Incoprea Theory
Vol. XXVI · 129

Theory 42/Fever cycle/Termination phase

Defervescence Is Clearance

The claim

Fever ends when the ratio of pyrogen clearance to production falls below one, so resolution is a clearance phenomenon and can be abrupt.

01Mechanism

Set point returns as pyrogen is removed; the ratio determines the rate.

02Prediction

Resolution rate should track clearance.

03Refutation

Resolution tracking time would remove clearance.