Theory 02/Cell division cycle/Progression phase
Progression Is Fork Against Damage
The claim
Cycle duration is set by the ratio of replication fork rate to the rate at which damage slows it, so a slow fork under damage arrests.
01Mechanism
Replication must finish before mitosis; slowing accumulates until a checkpoint fires.
02Prediction
Duration should track the rate ratio.
03Refutation
Duration tracking cell size would remove the fork term.