Incoprea Theory
Vol. XXIV · 219

Theory 74/Pain/Threshold lens

Chronic Pain Is a Threshold Shift

The claim

The transition to chronic pain occurs when central sensitisation lowers the threshold below normal input levels, so pain persists without ongoing injury.

01Mechanism

Sensitisation increases gain in the pain pathway; the threshold falls until ordinary signals suffice.

02Prediction

Chronicity should track threshold shift.

03Refutation

Chronicity tracking injury severity would remove sensitisation.