Theory 23/Cellular/Organelle positioning
Position Is Force Against Drag
The claim
Organelle position is set by the ratio of motor force to cytoplasmic drag, so a large organelle sits further from the nucleus at the same motor activity.
01Mechanism
Movement stops where motor force balances viscous resistance, which rises with organelle size and cytoplasm viscosity.
02Prediction
Position should track the force ratio.
03Refutation
Position tracking motor activity alone would remove drag.