Theory 41/Tissue/Inflammation
Inflammation Spread Is Diffusion Against Density
The claim
Whether inflammation stays local or spreads is set by the ratio of cytokine diffusion to cell density, so dense tissue confines a signal that sparse tissue lets spread.
01Mechanism
Cells absorb and relay signals; at high density the signal is consumed locally, at low density it travels.
02Prediction
Spread should track the ratio.
03Refutation
Spread tracking cytokine amount would remove density.