Incoprea Theory
Vol. XXI · 39

Theory 07/Damkohler Number/Wound healing

Healing Rate Is a Damkohler

The claim

Wound closure rate is set by the ratio of cell proliferation rate to nutrient transport rate, so a well-perfused wound heals faster even with the same cells.

01Mechanism

Cells must be supplied as they divide; when proliferation outpaces delivery, growth stalls at the diffusion limit.

02Prediction

Closure rate should track the Damkohler number.

03Refutation

Closure tracking cell density would remove transport.