Incoprea Theory
Vol. XVI · 99

Theory 75/Timing & Gating/Developmental biology

Organ Size Is Set in a Window

The claim

Final organ size is set by the growth rate within a developmental window rather than by total growth time, so early perturbation cannot be compensated later.

01Mechanism

Growth is fastest and most sensitive to regulation during a window; after it, the organ reaches its set point and further time adds little.

02Prediction

Perturbations inside the window should matter more than later ones.

03Refutation

Compensation across the whole period would remove the window.